The mechanism of benzene-induced leukemia: a hypothesis and speculations on the causes of leukemia.

An overall hypothesis for benzene-induced leukemia is proposed. Key components of the hypothesis include a) activation of benzene in the liver to phenolic metabolites; b) transport of these metabolites to the bone marrow and conversion to semiquinone radicals and quinones via peroxidase enzymes; c)...

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Bibliographic Details
Main Author: Smith, M T
Format: Online
Language:English
Published: 1996
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1469721/