Distinction of mutagenic carcinogens from a mutagenic noncarcinogen in the big blue transgenic mouse.
The aromatic amines 2,4-diaminotoluene (2,4-DAT) and 2,6-diaminotoluene (2,6-DAT) are structural isomers that have been extensively studied for their mutagenic and carcinogenic characteristics. Both compounds are rapidly absorbed after oral administration and are equally mutagenic in the Ames test;...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
1996
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1469641/ |