Fold Designability, Distribution, and Disease

Fold designability has been estimated by the number of families contained in that fold. Here, we show that among orthologous proteins, sequence divergence is higher for folds with greater numbers of families. Folds with greater numbers of families also tend to have families that appear more often in...

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Bibliographic Details
Main Authors: Wong, Philip, Frishman, Dmitrij
Format: Online
Language:English
Published: Public Library of Science 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456317/