A real-time PCR-based method for determining the surface coverage of thiol-capped oligonucleotides bound onto gold nanoparticles
Here we report a real-time PCR-based method for determining the surface coverage of dithiol-capped oligonucleotides bound onto gold nanoparticles alone and in tandem with antibody. The detection of gold nanoparticle-bound DNA is accomplished by targeting the oligonucleotide with primer and probe bin...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2006
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440878/ |