Antiestrogens Inhibit Xenoestrogen-Induced Brain Aromatase Activity but Do Not Prevent Xenoestrogen-Induced Feminization in Japanese Medaka (Oryzias latipes)

In fish, exposure to estrogen or estrogen-mimicking chemicals (xenoestrogens) during a critical period of development can irreversibly invert sex differentiation. In medaka, a male-to-female reversal upon exposure to a xenoestrogen is accompanied by an increase in brain aromatase expression and acti...

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Bibliographic Details
Main Authors: Kuhl, Adam J., Brouwer, Marius
Format: Online
Language:English
Published: National Institute of Environmental Health Sciences 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440771/