Mutational analysis of the potential catalytic residues of the VV G1L metalloproteinase

The vaccinia virus G1L open-reading frame is predicted to be a metalloproteinase based upon the presence of a conserved zinc-binding motif. Western blot analysis demonstrates G1L undergoes proteolytic processing during the course of infection, although the significance of this event is unknown. In o...

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Bibliographic Details
Main Authors: Honeychurch, Kady M, Byrd, Chelsea M, Hruby, Dennis E
Format: Online
Language:English
Published: BioMed Central 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1420270/