Hepatitis C Virus (HCV) Infection and Hepatic Steatosis
There are two discrete forms of steatosis that may be found in patients infected with hepatitis C virus (HCV). Metabolic steatosis can coexist with HCV, regardless of genotype, in patients with risk factors such as obesity, hyperlipidemia, and insulin resistance. The second form of hepatic steatosis...
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| Format: | Online |
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Ivyspring International Publisher
2006
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1415843/ |
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pubmed-14158432006-04-13 Hepatitis C Virus (HCV) Infection and Hepatic Steatosis Yoon, Eugene J. Hu, Ke-Qin Review There are two discrete forms of steatosis that may be found in patients infected with hepatitis C virus (HCV). Metabolic steatosis can coexist with HCV, regardless of genotype, in patients with risk factors such as obesity, hyperlipidemia, and insulin resistance. The second form of hepatic steatosis in HCV patients is a result of the direct cytopathic effect of genotype 3 viral infections. There have been proposed mechanisms for this process but it remains elusive. Both categories of steatosis tend to hasten the progression of liver fibrosis and therefore prompt recognition and management should be initiated in patients with HCV and steatosis. The authors review the current understanding of the relationship between hepatitis C infection and hepatic steatosis and discuss future research directions. Ivyspring International Publisher 2006-04-01 /pmc/articles/PMC1415843/ /pubmed/16614743 Text en © Ivyspring International Publisher. This is an open access article. Reproduction is permitted for personal and noncommerical use, provided that the article is in whole, unmodified, and properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Yoon, Eugene J. Hu, Ke-Qin |
| spellingShingle |
Yoon, Eugene J. Hu, Ke-Qin Hepatitis C Virus (HCV) Infection and Hepatic Steatosis |
| author_facet |
Yoon, Eugene J. Hu, Ke-Qin |
| author_sort |
Yoon, Eugene J. |
| title |
Hepatitis C Virus (HCV) Infection and Hepatic Steatosis |
| title_short |
Hepatitis C Virus (HCV) Infection and Hepatic Steatosis |
| title_full |
Hepatitis C Virus (HCV) Infection and Hepatic Steatosis |
| title_fullStr |
Hepatitis C Virus (HCV) Infection and Hepatic Steatosis |
| title_full_unstemmed |
Hepatitis C Virus (HCV) Infection and Hepatic Steatosis |
| title_sort |
hepatitis c virus (hcv) infection and hepatic steatosis |
| description |
There are two discrete forms of steatosis that may be found in patients infected with hepatitis C virus (HCV). Metabolic steatosis can coexist with HCV, regardless of genotype, in patients with risk factors such as obesity, hyperlipidemia, and insulin resistance. The second form of hepatic steatosis in HCV patients is a result of the direct cytopathic effect of genotype 3 viral infections. There have been proposed mechanisms for this process but it remains elusive. Both categories of steatosis tend to hasten the progression of liver fibrosis and therefore prompt recognition and management should be initiated in patients with HCV and steatosis. The authors review the current understanding of the relationship between hepatitis C infection and hepatic steatosis and discuss future research directions. |
| publisher |
Ivyspring International Publisher |
| publishDate |
2006 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1415843/ |
| _version_ |
1611381529637814272 |