M-Coffee: combining multiple sequence alignment methods with T-Coffee

We introduce M-Coffee, a meta-method for assembling multiple sequence alignments (MSA) by combining the output of several individual methods into one single MSA. M-Coffee is an extension of T-Coffee and uses consistency to estimate a consensus alignment. We show that the procedure is robust to varia...

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Bibliographic Details
Main Authors: Wallace, Iain M., O'Sullivan, Orla, Higgins, Desmond G., Notredame, Cedric
Format: Online
Language:English
Published: Oxford University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1410914/