Therapeutic androgen receptor ligands

In the past several years, the concept of tissue-selective nuclear receptor ligands has emerged. This concept has come to fruition with estrogens, with the successful marketing of drugs such as raloxifene. The discovery of raloxifene and other selective estrogen receptor modulators (SERMs) has raise...

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Main Authors: Allan, George F., Sui, Zhihua
Format: Online
Language:English
Published: The Nuclear Receptor Signaling Atlas 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402218/
id pubmed-1402218
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spelling pubmed-14022182006-04-06 Therapeutic androgen receptor ligands Allan, George F. Sui, Zhihua Review In the past several years, the concept of tissue-selective nuclear receptor ligands has emerged. This concept has come to fruition with estrogens, with the successful marketing of drugs such as raloxifene. The discovery of raloxifene and other selective estrogen receptor modulators (SERMs) has raised the possibility of generating selective compounds for other pathways, including androgens (that is, selective androgen receptor modulators, or SARMs). The Nuclear Receptor Signaling Atlas 2003-09-27 /pmc/articles/PMC1402218/ /pubmed/16604181 http://dx.doi.org/10.1621/nrs.01009 Text en Copyright © 2003, Allan and Sui. This is an open-access article distributed under the terms of the Creative Commons Non-Commercial Attribution License, which permits unrestricted non-commercial use distribution and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Allan, George F.
Sui, Zhihua
spellingShingle Allan, George F.
Sui, Zhihua
Therapeutic androgen receptor ligands
author_facet Allan, George F.
Sui, Zhihua
author_sort Allan, George F.
title Therapeutic androgen receptor ligands
title_short Therapeutic androgen receptor ligands
title_full Therapeutic androgen receptor ligands
title_fullStr Therapeutic androgen receptor ligands
title_full_unstemmed Therapeutic androgen receptor ligands
title_sort therapeutic androgen receptor ligands
description In the past several years, the concept of tissue-selective nuclear receptor ligands has emerged. This concept has come to fruition with estrogens, with the successful marketing of drugs such as raloxifene. The discovery of raloxifene and other selective estrogen receptor modulators (SERMs) has raised the possibility of generating selective compounds for other pathways, including androgens (that is, selective androgen receptor modulators, or SARMs).
publisher The Nuclear Receptor Signaling Atlas
publishDate 2003
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402218/
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