Therapeutic androgen receptor ligands
In the past several years, the concept of tissue-selective nuclear receptor ligands has emerged. This concept has come to fruition with estrogens, with the successful marketing of drugs such as raloxifene. The discovery of raloxifene and other selective estrogen receptor modulators (SERMs) has raise...
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The Nuclear Receptor Signaling Atlas
2003
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402218/ |
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pubmed-14022182006-04-06 Therapeutic androgen receptor ligands Allan, George F. Sui, Zhihua Review In the past several years, the concept of tissue-selective nuclear receptor ligands has emerged. This concept has come to fruition with estrogens, with the successful marketing of drugs such as raloxifene. The discovery of raloxifene and other selective estrogen receptor modulators (SERMs) has raised the possibility of generating selective compounds for other pathways, including androgens (that is, selective androgen receptor modulators, or SARMs). The Nuclear Receptor Signaling Atlas 2003-09-27 /pmc/articles/PMC1402218/ /pubmed/16604181 http://dx.doi.org/10.1621/nrs.01009 Text en Copyright © 2003, Allan and Sui. This is an open-access article distributed under the terms of the Creative Commons Non-Commercial Attribution License, which permits unrestricted non-commercial use distribution and reproduction in any medium, provided the original work is properly cited. |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Allan, George F. Sui, Zhihua |
spellingShingle |
Allan, George F. Sui, Zhihua Therapeutic androgen receptor ligands |
author_facet |
Allan, George F. Sui, Zhihua |
author_sort |
Allan, George F. |
title |
Therapeutic androgen receptor ligands |
title_short |
Therapeutic androgen receptor ligands |
title_full |
Therapeutic androgen receptor ligands |
title_fullStr |
Therapeutic androgen receptor ligands |
title_full_unstemmed |
Therapeutic androgen receptor ligands |
title_sort |
therapeutic androgen receptor ligands |
description |
In the past several years, the concept of tissue-selective nuclear receptor ligands has emerged. This concept has come to fruition with estrogens, with the successful marketing of drugs such as raloxifene. The discovery of raloxifene and other selective estrogen receptor modulators (SERMs) has raised the possibility of generating selective compounds for other pathways, including androgens (that is, selective androgen receptor modulators, or SARMs). |
publisher |
The Nuclear Receptor Signaling Atlas |
publishDate |
2003 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402218/ |
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1611381228380880896 |