Caretaker Brca1: keeping the genome in the straight and narrow
Inheritance of germline BRCA1 mutations is associated with a high risk of breast and ovarian cancers. A multitude of cellular functions has been ascribed to BRCA1, including transcription activation and various aspects of DNA repair. So far, indirect evidence has indicated a role for BRCA1 in the re...
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| Format: | Online |
| Language: | English |
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BioMed Central
2000
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139427/ |