The human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activity
Telomeres, the protein–DNA complexes at the ends of eukaryotic chromosomes, are essential for chromosome stability, and their maintenance is achieved by the specialized reverse transcriptase activity of telomerase or the homologous recombination pathway in most eukaryotes. Here, we identified a huma...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2006
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1390689/ |