The p53 pathway in breast cancer

p53 mutation remains the most common genetic change identified in human neoplasia. In breast cancer, p53 mutation is associated with more aggressive disease and worse overall survival. The frequency of mutation in p53 is, however, lower in breast cancer than in other solid tumours. Changes, both gen...

Full description

Bibliographic Details
Main Authors: Gasco, Milena, Shami, Shukri, Crook, Tim
Format: Online
Language:English
Published: BioMed Central 2002
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138723/