Role of BRCA gene dysfunction in breast and ovarian cancer predisposition
Tumor suppressor genes that perform apparently generic cellular functions nonetheless cause tissue-specific syndromes in the human population when they are mutated in the germline. The two major hereditary breast/ovarian cancer predisposition genes, BRCA1 and BRCA2, appear to participate in a common...
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| Format: | Online |
| Language: | English |
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BioMed Central
2000
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138653/ |