Isolation of a site-specifically modified RNA from an unmodified transcript

Natural RNAs contain many base modifications that have specific biological functions. The ability to functionally dissect individual modifications is facilitated by the identification and cloning of enzymes responsible for these modifications, but is hindered by the difficulty of isolating site-spec...

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Bibliographic Details
Main Authors: Hou, Ya-Ming, Li, Zhi, Gamper, Howard
Format: Online
Language:English
Published: Oxford University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1363780/