Sequence effects of aminofluorene-modified DNA duplexes: thermodynamic and circular dichroism properties

Circular dichroism (CD) and UV-melting experiments were conducted with 16 oligodeoxynucleotides modified by the carcinogen 2-aminofluorene, whose sequence around the lesion was varied systematically [d(CTTCTNG[AF]NCCTC), N = G, A, C, T], to gain insight into the factors that determine the equilibriu...

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Bibliographic Details
Main Authors: Meneni, Srinivasa Rao, D'Mello, Rhijuta, Norigian, Gregory, Baker, Gregory, Gao, Lan, Chiarelli, M. Paul, Cho, Bongsup P.
Format: Online
Language:English
Published: Oxford University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356535/