Hfq variant with altered RNA binding functions

The interaction between Hfq and RNA is central to multiple regulatory processes. Using site-directed mutagenesis, we have found a missense mutation in Hfq (V43R) which strongly affects2 the RNA binding capacity of the Hfq protein and its ability to stimulate poly(A) tail elongation by poly(A)-polyme...

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Bibliographic Details
Main Authors: Ziolkowska, Katarzyna, Derreumaux, Philippe, Folichon, Marc, Pellegrini, Olivier, Régnier, Philippe, Boni, Irina V., Hajnsdorf, Eliane
Format: Online
Language:English
Published: Oxford University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356530/