Nucleic acid binding and chaperone properties of HIV-1 Gag and nucleocapsid proteins

The Gag polyprotein of HIV-1 is essential for retroviral replication and packaging. The nucleocapsid (NC) protein is the primary region for the interaction of Gag with nucleic acids. In this study, we examine the interactions of Gag and its NC cleavage products (NCp15, NCp9 and NCp7) with nucleic ac...

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Bibliographic Details
Main Authors: Cruceanu, Margareta, Urbaneja, Maria A., Hixson, Catherine V., Johnson, Donald G., Datta, Siddhartha A., Fivash, Matthew J., Stephen, Andrew G., Fisher, Robert J., Gorelick, Robert J., Casas-Finet, Jose R., Rein, Alan, Rouzina, Ioulia, Williams, Mark C.
Format: Online
Language:English
Published: Oxford University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356529/