Hierarchical clustering algorithm for comprehensive orthologous-domain classification in multiple genomes

Ortholog identification is a crucial first step in comparative genomics. Here, we present a rapid method of ortholog grouping which is effective enough to allow the comparison of many genomes simultaneously. The method takes as input all-against-all similarity data and classifies genes based on the...

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Bibliographic Details
Main Author: Uchiyama, Ikuo
Format: Online
Language:English
Published: Oxford University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1351371/