Oligomerization of HEXIM1 via 7SK snRNA and coiled-coil region directs the inhibition of P-TEFb

Oligomerization of HEXIM1 via 7SK snRNA and coiled-coil region directs the inhibition of P-TEFb

Transcriptional elongation of most eukaryotic genes by RNA polymerase II requires the kinase activity of the positive transcription elongation factor b (P-TEFb). The catalytically active P-TEFb complex becomes inactive when sequestered into the large complex by the cooperative actions of 7SK snRNA a...

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Bibliographic Details
Main Authors: Blazek, Dalibor, Barboric, Matjaz, Kohoutek, Jiri, Oven, Irena, Peterlin, B. Matija
Format: Online
Language:English
Published: Oxford University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1322273/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1322273/

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