Science review: Carnitine in the treatment of valproic acid-induced toxicity – what is the evidence?

Valproic acid (VPA) is a broad-spectrum antiepileptic drug and is usually well tolerated, but rare serious complications may occur in some patients receiving VPA chronically, including haemorrhagic pancreatitis, bone marrow suppression, VPA-induced hepatotoxicity (VHT) and VPA-induced hyperammonaemi...

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Bibliographic Details
Main Authors: Lheureux, Philippe ER, Penaloza, Andrea, Zahir, Soheil, Gris, Mireille
Format: Online
Language:English
Published: BioMed Central 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297603/