Effects of Hypothalamic Neurodegeneration on Energy Balance
Normal aging in humans and rodents is accompanied by a progressive increase in adiposity. To investigate the role of hypothalamic neuronal circuits in this process, we used a Cre-lox strategy to create mice with specific and progressive degeneration of hypothalamic neurons that express agouti-relate...
Main Authors: | , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2005
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1287504/ |