Systematic Discovery of New Recognition Peptides Mediating Protein Interaction Networks

Many aspects of cell signalling, trafficking, and targeting are governed by interactions between globular protein domains and short peptide segments. These domains often bind multiple peptides that share a common sequence pattern, or “linear motif” (e.g., SH3 binding to PxxP). Many domains are known...

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Bibliographic Details
Main Authors: Neduva, Victor, Linding, Rune, Su-Angrand, Isabelle, Stark, Alexander, de Masi, Federico, Gibson, Toby J, Lewis, Joe, Serrano, Luis, Russell, Robert B
Format: Online
Language:English
Published: Public Library of Science 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1283537/