Computational discovery of sense-antisense transcription in the human and mouse genomes

Overlapping but oppositely oriented transcripts have the potential to form sense-antisense perfect double-stranded (ds) RNA duplexes. A bioinformatics approach has identified over 217 candidate overlapping transcriptional units, bringing the total number of predicted and validated examples of overla...

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Main Authors: Shendure, Jay, Church, George M
Format: Online
Language:English
Published: BioMed Central 2002
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC126869/
id pubmed-126869
recordtype oai_dc
spelling pubmed-1268692002-10-09 Computational discovery of sense-antisense transcription in the human and mouse genomes Shendure, Jay Church, George M Research Overlapping but oppositely oriented transcripts have the potential to form sense-antisense perfect double-stranded (ds) RNA duplexes. A bioinformatics approach has identified over 217 candidate overlapping transcriptional units, bringing the total number of predicted and validated examples of overlapping but oppositely oriented transcripts to over 300. BioMed Central 2002 2002-08-22 /pmc/articles/PMC126869/ /pubmed/12225583 Text en Copyright © 2002 Shendure and Church, licensee BioMed Central Ltd
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Shendure, Jay
Church, George M
spellingShingle Shendure, Jay
Church, George M
Computational discovery of sense-antisense transcription in the human and mouse genomes
author_facet Shendure, Jay
Church, George M
author_sort Shendure, Jay
title Computational discovery of sense-antisense transcription in the human and mouse genomes
title_short Computational discovery of sense-antisense transcription in the human and mouse genomes
title_full Computational discovery of sense-antisense transcription in the human and mouse genomes
title_fullStr Computational discovery of sense-antisense transcription in the human and mouse genomes
title_full_unstemmed Computational discovery of sense-antisense transcription in the human and mouse genomes
title_sort computational discovery of sense-antisense transcription in the human and mouse genomes
description Overlapping but oppositely oriented transcripts have the potential to form sense-antisense perfect double-stranded (ds) RNA duplexes. A bioinformatics approach has identified over 217 candidate overlapping transcriptional units, bringing the total number of predicted and validated examples of overlapping but oppositely oriented transcripts to over 300.
publisher BioMed Central
publishDate 2002
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC126869/
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