Regulation of IκBα expression involves both NF-κB and the MAP kinase signaling pathways

Regulation of IκBα expression involves both NF-κB and the MAP kinase signaling pathways

IκBα is an inhibitor of the nuclear transcription factor NF-κB. Binding of IκBα to NF-κB inactivates the transcriptional activity of NF-κB. Expression of IκBα itself is regulated by NF-κB, which provides auto-regulation of this signaling pathway. Here we present a mouse model for monitoring in vivo...

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Bibliographic Details
Main Authors: Zhang, Ning, Ahsan, Muhammad H, Zhu, Lingyun, Sambucetti, Lidia C, Purchio, Anthony F, West, David B
Format: Online
Language:English
Published: BioMed Central 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1262753/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1262753/

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