Gene-expression profiling of the response of peripheral blood mononuclear cells and melanoma metastases to systemic IL-2 administration

Early changes in transcriptional profiles of circulating mononuclear cells were compared with those occurring within the microenvironment of melanoma metastases following systemic IL-2 administration. The results suggest that the immediate effects of IL-2 administration on the tumor microenvironment...

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Bibliographic Details
Main Authors: Panelli, Monica C, Wang, Ena, Phan, Giao, Puhlmann, Markus, Miller, Lance, Ohnmacht, Galen A, Klein, Harvey G, Marincola, Francesco M
Format: Online
Language:English
Published: BioMed Central 2002
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC126240/