Lead Exposure Inhibits Fracture Healing and Is Associated with Increased Chondrogenesis, Delay in Cartilage Mineralization, and a Decrease in Osteoprogenitor Frequency

Lead exposure continues to be a significant public health problem. In addition to acute toxicity, Pb has an extremely long half-life in bone. Individuals with past exposure develop increased blood Pb levels during periods of high bone turnover or resorption. Pb is known to affect osteoblasts, osteoc...

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Bibliographic Details
Main Authors: Carmouche, Jonathan J., Puzas, J. Edward, Zhang, Xinping, Tiyapatanaputi, Prarop, Cory-Slechta, Deborah A., Gelein, Robert, Zuscik, Michael, Rosier, Randy N., Boyce, Brendan F., O’Keefe, Regis J., Schwarz, Edward M.
Format: Online
Language:English
Published: National Institue of Environmental Health Sciences 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1257601/