Rapid detection of genomic imbalances using micro-arrays consisting of pooled BACs covering all human chromosome arms

A strategy is presented to select, pool and spot human BAC clones on an array in such a way that each spot contains five well performing BAC clones, covering one chromosome arm. A mini-array of 240 spots was prepared representing all human chromosome arms in a 5-fold as well as some controls, and us...

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Bibliographic Details
Main Authors: Knijnenburg, Jeroen, van der Burg, Marja, Nilsson, Philomeen, van Amstel, Hans Kristian Ploos, Tanke, Hans, Szuhai, Károly
Format: Online
Language:English
Published: Oxford University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253841/