Dose-Additive Carcinogenicity of a Defined Mixture of “Dioxin-like Compounds”

Use of the dioxin toxic equivalency factor (TEF) approach in human risk assessments assumes that the combined effects of dioxin-like compounds in a mixture can be predicted based on a potency-adjusted dose-additive combination of constituents of the mixture. In this study, we evaluated the TEF appro...

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Bibliographic Details
Main Authors: Walker, Nigel J., Crockett, Patrick W., Nyska, Abraham, Brix, Amy E., Jokinen, Michael P., Sells, Donald M., Hailey, James R., Easterling, Micheal, Haseman, Joseph K., Yin, Ming, Wyde, Michael E., Bucher, John R., Portier, Christopher J.
Format: Online
Language:English
Published: National Institue of Environmental Health Sciences 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253708/