Reproducible doxycycline-inducible transgene expression at specific loci generated by Cre-recombinase mediated cassette exchange
Comparative analysis of mutants using transfection is complicated by clones exhibiting variable levels of gene expression due to copy number differences and genomic position effects. Recombinase-mediated cassette exchange (RMCE) can overcome these problems by introducing the target gene into pre-det...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2005
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1243804/ |