Developmental increases in rat hepatic microsomal UDP-glucuronosyltransferase activities toward xenoestrogens and decreases during pregnancy.
Xenoestrogens, such as bisphenol A and diethylstilbestrol, are glucuronidated by an isoform of UDP-glucuronosyltransferase named UGT2B1 in the livers of adult male rats. In this study, we found that nonylphenol and octylphenol are also conjugated with glucuronic acid by adult rat liver microsomes. A...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
2002
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240735/ |