Irreversible binding and adrenocorticolytic activity of the DDT metabolite 3-methylsulfonyl-DDE examined in tissue-slice culture.

Irreversible binding and adrenocorticolytic activity of the DDT metabolite 3-methylsulfonyl-DDE examined in tissue-slice culture.

The persistent adrenocorticolytic DDT metabolite 3-methylsulfonyl-DDE (MeSO(2)-DDE) was originally identified in Baltic grey seals, a population suffering from adrenocortical hyperplasia. In mice, MeSO(2)-DDE induces mitochondrial degeneration and cellular necrosis in the adrenal zona fasciculata. I...

Full description

Bibliographic Details
Main Authors: Lindhe , O, Lund, B O, Bergman , A, Brandt, I
Format: Online
Language:English
Published: National Institute of Environmental Health Science 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240628/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240628/

Similar Items