Influenza Virus PB1-F2 Protein Induces Cell Death through Mitochondrial ANT3 and VDAC1

The influenza virus PB1-F2 is an 87-amino acid mitochondrial protein that previously has been shown to induce cell death, although the mechanism of apoptosis induction has remained unclear. In the process of characterizing its mechanism of action we found that the viral PB1-F2 protein sensitizes cel...

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Bibliographic Details
Main Authors: Zamarin, Dmitriy, GarcĂ­a-Sastre, Adolfo, Xiao, Xiaoyao, Wang, Rong, Palese, Peter
Format: Online
Language:English
Published: Public Library of Science 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1238739/