A thermodynamic approach to designing structure-free combinatorial DNA word sets

A thermodynamic approach to designing structure-free combinatorial DNA word sets

An algorithm is presented for the generation of sets of non-interacting DNA sequences, employing existing thermodynamic models for the prediction of duplex stabilities and secondary structures. A DNA ‘word’ structure is employed in which individual DNA ‘words’ of a given length (e.g. 12mer and 16mer...

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Bibliographic Details
Main Authors: Shortreed, Michael R., Chang, Seo Bong, Hong, DongGee, Phillips, Maggie, Campion, Bridget, Tulpan, Dan C., Andronescu, Mirela, Condon, Anne, Hoos, Holger H., Smith, Lloyd M.
Format: Online
Language:English
Published: Oxford University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1199559/

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