Efficient isothermal expansion of human telomeric and minisatellite repeats by Thermococcus litoralis DNA polymerase
Repeating DNA sequences, such as telomeres, centromeres, and micro- and mini-satellites, comprise 50% of the genome and play important roles in regulatory and pathogenic mechanisms. In order to study structures and functions of such repeating sequences, it is important to have simple and efficient m...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2005
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1199558/ |