Medium-Chain Acyl-CoA Dehydrogenase Deficiency in Gene-Targeted Mice

Medium-Chain Acyl-CoA Dehydrogenase Deficiency in Gene-Targeted Mice

Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency is the most common inherited disorder of mitochondrial fatty acid β-oxidation in humans. To better understand the pathogenesis of this disease, we developed a mouse model for MCAD deficiency (MCAD−/−) by gene targeting in embryonic stem (ES) cell...

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Bibliographic Details
Main Authors: Tolwani, Ravi J, Hamm, Doug A, Tian, Liqun, Sharer, J. Daniel, Vockley, Jerry, Rinaldo, Piero, Matern, Dietrich, Schoeb, Trenton R, Wood, Philip A
Format: Online
Language:English
Published: Public Library of Science 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1189074/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1189074/

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