Immune response to pneumococcal polysaccharides 4 and 14 in elderly and young adults. I Antibody concentrations, avidity and functional activity

Streptococcus pneumoniae is a serious worldwide pathogen and the focus of numerous vaccine development projects. Currently the most widely accepted surrogate marker for evaluating the efficacy of a given vaccine is to utilize ELISA. Measurement of antibody concentration by ELISA without reduction in...

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Bibliographic Details
Main Authors: Kolibab, Kris, Smithson, S Louise, Shriner, Anne K, Khuder, Sadik, Romero-Steiner, Sandra, Carlone, George M, Westerink, MA Julie
Format: Online
Language:English
Published: BioMed Central 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184095/