New Genes Tied to Endocrine, Metabolic, and Dietary Regulation of Lifespan from a Caenorhabditis elegans Genomic RNAi Screen

Most of our knowledge about the regulation of aging comes from mutants originally isolated for other phenotypes. To ask whether our current view of aging has been affected by selection bias, and to deepen our understanding of known longevity pathways, we screened a genomic Caenorhabditis elegans RNA...

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Bibliographic Details
Main Authors: Hansen, Malene, Hsu, Ao-Lin, Dillin, Andrew, Kenyon, Cynthia
Format: Online
Language:English
Published: Public Library of Science 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1183531/