Stitchprofiles.uio.no: analysis of partly melted DNA conformations using stitch profiles
In this study, we describe a web server that performs computations on DNA melting, thus predicting the localized separation of the two strands for sequences provided by the users. The output types are stitch profiles, melting curves, probability profiles, etc. Stitch profile diagrams visualize the e...
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pubmed-11601852005-06-29 Stitchprofiles.uio.no: analysis of partly melted DNA conformations using stitch profiles Tøstesen, Eivind Jerstad, Geir Ivar Hovig, Eivind Article In this study, we describe a web server that performs computations on DNA melting, thus predicting the localized separation of the two strands for sequences provided by the users. The output types are stitch profiles, melting curves, probability profiles, etc. Stitch profile diagrams visualize the ensemble of alternative conformations that DNA can adopt with different probabilities. For example, a stitch profile shows the possible loop openings in terms of their locations, sizes, probabilities and fluctuations at a given temperature. Sequences with lengths up to several tens or hundreds of kilobase pairs can be analysed. The tools are freely available at . Oxford University Press 2005-07-01 2005-06-27 /pmc/articles/PMC1160185/ /pubmed/15980539 http://dx.doi.org/10.1093/nar/gki424 Text en © The Author 2005. Published by Oxford University Press. All rights reserved |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Tøstesen, Eivind Jerstad, Geir Ivar Hovig, Eivind |
spellingShingle |
Tøstesen, Eivind Jerstad, Geir Ivar Hovig, Eivind Stitchprofiles.uio.no: analysis of partly melted DNA conformations using stitch profiles |
author_facet |
Tøstesen, Eivind Jerstad, Geir Ivar Hovig, Eivind |
author_sort |
Tøstesen, Eivind |
title |
Stitchprofiles.uio.no: analysis of partly melted DNA conformations using stitch profiles |
title_short |
Stitchprofiles.uio.no: analysis of partly melted DNA conformations using stitch profiles |
title_full |
Stitchprofiles.uio.no: analysis of partly melted DNA conformations using stitch profiles |
title_fullStr |
Stitchprofiles.uio.no: analysis of partly melted DNA conformations using stitch profiles |
title_full_unstemmed |
Stitchprofiles.uio.no: analysis of partly melted DNA conformations using stitch profiles |
title_sort |
stitchprofiles.uio.no: analysis of partly melted dna conformations using stitch profiles |
description |
In this study, we describe a web server that performs computations on DNA melting, thus predicting the localized separation of the two strands for sequences provided by the users. The output types are stitch profiles, melting curves, probability profiles, etc. Stitch profile diagrams visualize the ensemble of alternative conformations that DNA can adopt with different probabilities. For example, a stitch profile shows the possible loop openings in terms of their locations, sizes, probabilities and fluctuations at a given temperature. Sequences with lengths up to several tens or hundreds of kilobase pairs can be analysed. The tools are freely available at . |
publisher |
Oxford University Press |
publishDate |
2005 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160185/ |
_version_ |
1611375455061934080 |