Aquaporins in development – a review
Water homeostasis during fetal development is of crucial physiologic importance. It depends upon maternal fetal fluid exchange at the placenta and fetal membranes, and some exchange between fetus and amniotic fluid can occur across the skin before full keratinization. Lungs only grow and develop nor...
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| Format: | Online |
| Language: | English |
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BioMed Central
2005
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1156947/ |
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pubmed-11569472005-06-22 Aquaporins in development – a review Liu, Huishu Wintour, E Marelyn Review Water homeostasis during fetal development is of crucial physiologic importance. It depends upon maternal fetal fluid exchange at the placenta and fetal membranes, and some exchange between fetus and amniotic fluid can occur across the skin before full keratinization. Lungs only grow and develop normally with fluid secretion, and there is evidence that cerebral spinal fluid formation is important in normal brain development. The aquaporins are a growing family of molecular water channels, the ontogeny of which is starting to be explored. One question that is of particular importance is how well does the rodent (mouse, rat) fetus serve as a model for long-gestation mammals such as sheep and human? This is particularly important for organs such as the lung and the kidney, whose development before birth is very much less in rodents than in the long-gestation species. BioMed Central 2005-05-11 /pmc/articles/PMC1156947/ /pubmed/15888206 http://dx.doi.org/10.1186/1477-7827-3-18 Text en Copyright © 2005 Liu and Wintour; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Liu, Huishu Wintour, E Marelyn |
| spellingShingle |
Liu, Huishu Wintour, E Marelyn Aquaporins in development – a review |
| author_facet |
Liu, Huishu Wintour, E Marelyn |
| author_sort |
Liu, Huishu |
| title |
Aquaporins in development – a review |
| title_short |
Aquaporins in development – a review |
| title_full |
Aquaporins in development – a review |
| title_fullStr |
Aquaporins in development – a review |
| title_full_unstemmed |
Aquaporins in development – a review |
| title_sort |
aquaporins in development – a review |
| description |
Water homeostasis during fetal development is of crucial physiologic importance. It depends upon maternal fetal fluid exchange at the placenta and fetal membranes, and some exchange between fetus and amniotic fluid can occur across the skin before full keratinization. Lungs only grow and develop normally with fluid secretion, and there is evidence that cerebral spinal fluid formation is important in normal brain development. The aquaporins are a growing family of molecular water channels, the ontogeny of which is starting to be explored. One question that is of particular importance is how well does the rodent (mouse, rat) fetus serve as a model for long-gestation mammals such as sheep and human? This is particularly important for organs such as the lung and the kidney, whose development before birth is very much less in rodents than in the long-gestation species. |
| publisher |
BioMed Central |
| publishDate |
2005 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1156947/ |
| _version_ |
1611375380723138560 |