RNA interference by mixtures of siRNAs prepared using custom oligonucleotide arrays

RNA interference (RNAi) is a process in which double-strand RNA (dsRNA) directs the specific degradation of a corresponding target mRNA. The mediators of this process are small dsRNAs, of ∼21 bp in length, called small interfering RNAs (siRNAs). siRNAs, which can be prepared in vitro in a number of...

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Bibliographic Details
Main Authors: Oleinikov, Andrew V., Zhao, Jun, Gray, Matthew D.
Format: Online
Language:English
Published: Oxford University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1143701/