The third helix of the homeodomain of paired class homeodomain proteins acts as a recognition helix both for DNA and protein interactions

The transcription factor Pax6 is essential for the development of the eyes and the central nervous system of vertebrates and invertebrates. Pax6 contains two DNA-binding domains; an N-terminal paired domain and a centrally located homeodomain. We have previously shown that the vertebrate paired-less...

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Bibliographic Details
Main Authors: Bruun, Jack-Ansgar, Thomassen, Ernst Ivan Simon, Kristiansen, Kurt, Tylden, Garth, Holm, Turid, Mikkola, Ingvild, Bjørkøy, Geir, Johansen, Terje
Format: Online
Language:English
Published: Oxford University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1092277/