Antigen-Engaged B Cells Undergo Chemotaxis toward the T Zone and Form Motile Conjugates with Helper T Cells
Interactions between B and T cells are essential for most antibody responses, but the dynamics of these interactions are poorly understood. By two-photon microscopy of intact lymph nodes, we show that upon exposure to antigen, B cells migrate with directional preference toward the B-zone–T-zone boun...
Main Authors: | , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2005
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1088276/ |