Endocrinology and hormone therapy in breast cancer: Aromatase inhibitors versus antioestrogens

Endocrine therapies act by either blocking or downregulating the oestrogen receptor or by reducing oestrogen concentrations around and within the cancer cell. In postmenopausal women, oestrogen suppression is achieved by inhibition of the enzyme aromatase by aromatase inhibitors (AIs). Modern AIs (a...

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Bibliographic Details
Main Authors: Howell, Anthony, Dowsett, Mitch
Format: Online
Language:English
Published: BioMed Central 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064088/