Inhibition of GSK3 attenuates the intracellular multiplication of burkholderia pseudomallei and modulates the inflammatory response in infected macrophages and A549 epithelial lung cells

Burkholderia pseudomallei, the causative agent of melioidosis, is an intracellular pathogen capable of invading and multiplying in both phagocytic and non-phagocytic cells. Infection results in an inflammatory response involving production of both pro- and anti-inflammatory cytokines. The cellular m...

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Bibliographic Details
Main Authors: Pramila Maniam, Aishah Farliani Shirat, Hasidah Mohd Sidek, Ghazally Ismail, Noor Embi
Format: Article
Language:English
Published: Universiti Kebangsaan Malaysia 2013
Online Access:http://journalarticle.ukm.my/6275/
http://journalarticle.ukm.my/6275/
http://journalarticle.ukm.my/6275/1/04_Pramila_Maniam.pdf