Potentiation of latent inhibition by haloperidol and clozapine is attenuated in Dopamine D2 receptor (Drd-2) deficient mice: Do antipsychotics influence learning to ignore irrelevant stimuli via both Drd-2 and non-Drd-2 mechanisms?
Whether the dopamine Drd-2 receptor is necessary for the behavioural action of antipsychotic drugs is an important question, as Drd-2 antagonism is responsible for their debilitating motor side effects. Using Drd-2 null mice (Drd2 -/-) it has previously been shown that Drd-2 is not necessary for ant...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sage
2014
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| Online Access: | http://eprints.nottingham.ac.uk/52889/ http://eprints.nottingham.ac.uk/52889/ http://eprints.nottingham.ac.uk/52889/ http://eprints.nottingham.ac.uk/52889/7/0269881114544774.pdf |