How to characterize the function of a brain region

Many brain regions have been defined, but a comprehensive formalization of each region’s function in relation to human behavior is still lacking. Current knowledge comes from various fields, which have diverse conceptions of ‘functions’. We briefly review these fields and outline how the heterogenei...

Full description

Bibliographic Details
Main Authors:	Genon, Sarah, Reid, Andrew, Langner, Robert, Amunts, Katrin, Eickhoff, Simon B.
Format:	Article
Language:	English
Published:	Elsevier 2018
Online Access:	http://eprints.nottingham.ac.uk/51332/ http://eprints.nottingham.ac.uk/51332/ http://eprints.nottingham.ac.uk/51332/ http://eprints.nottingham.ac.uk/51332/7/1-s2.0-S1364661318300238-main.pdf

id	nottingham-51332
recordtype	eprints
spelling	nottingham-513322018-04-24T08:22:17Z http://eprints.nottingham.ac.uk/51332/ How to characterize the function of a brain region Genon, Sarah Reid, Andrew Langner, Robert Amunts, Katrin Eickhoff, Simon B. Many brain regions have been defined, but a comprehensive formalization of each region’s function in relation to human behavior is still lacking. Current knowledge comes from various fields, which have diverse conceptions of ‘functions’. We briefly review these fields and outline how the heterogeneity of associations could be harnessed to disclose the computational function of any region. Aggregating activation data from neuroimaging studies allows us to characterize the functional engagement of a region across a range of experimental conditions. Furthermore, large-sample data can disclose covariation between brain region features and ecological behavioral phenotyping. Combining these two approaches opens a new perspective to determine the behavioral associations of a brain region, and hence its function and broader role within large-scale functional networks. Elsevier 2018-04-30 Article PeerReviewed application/pdf en cc_by http://eprints.nottingham.ac.uk/51332/7/1-s2.0-S1364661318300238-main.pdf Genon, Sarah and Reid, Andrew and Langner, Robert and Amunts, Katrin and Eickhoff, Simon B. (2018) How to characterize the function of a brain region. Trends in Cognitive Sciences, 22 (4). pp. 350-364. ISSN 1879-307X https://doi.org/10.1016/j.tics.2018.01.010 doi:10.1016/j.tics.2018.01.010 doi:10.1016/j.tics.2018.01.010
repository_type	Digital Repository
institution_category	Local University
institution	University of Nottingham Malaysia Campus
building	Nottingham Research Data Repository
collection	Online Access
language	English
description	Many brain regions have been defined, but a comprehensive formalization of each region’s function in relation to human behavior is still lacking. Current knowledge comes from various fields, which have diverse conceptions of ‘functions’. We briefly review these fields and outline how the heterogeneity of associations could be harnessed to disclose the computational function of any region. Aggregating activation data from neuroimaging studies allows us to characterize the functional engagement of a region across a range of experimental conditions. Furthermore, large-sample data can disclose covariation between brain region features and ecological behavioral phenotyping. Combining these two approaches opens a new perspective to determine the behavioral associations of a brain region, and hence its function and broader role within large-scale functional networks.
format	Article
author	Genon, Sarah Reid, Andrew Langner, Robert Amunts, Katrin Eickhoff, Simon B.
spellingShingle	Genon, Sarah Reid, Andrew Langner, Robert Amunts, Katrin Eickhoff, Simon B. How to characterize the function of a brain region
author_facet	Genon, Sarah Reid, Andrew Langner, Robert Amunts, Katrin Eickhoff, Simon B.
author_sort	Genon, Sarah
title	How to characterize the function of a brain region
title_short	How to characterize the function of a brain region
title_full	How to characterize the function of a brain region
title_fullStr	How to characterize the function of a brain region
title_full_unstemmed	How to characterize the function of a brain region
title_sort	how to characterize the function of a brain region
publisher	Elsevier
publishDate	2018
url	http://eprints.nottingham.ac.uk/51332/ http://eprints.nottingham.ac.uk/51332/ http://eprints.nottingham.ac.uk/51332/ http://eprints.nottingham.ac.uk/51332/7/1-s2.0-S1364661318300238-main.pdf
first_indexed	2018-09-06T14:20:00Z
last_indexed	2018-09-06T14:20:00Z
_version_	1610868170139107328

How to characterize the function of a brain region

Similar Items