Loss of epithelial Gq and G11 signaling inhibits TGFbeta production but promotes IL-33-mediated macrophage polarization and emphysema
Heterotrimeric guanine nucleotide-binding protein (G protein) signaling links hundreds of G protein-coupled receptors with four G protein signaling pathways. Two of these, one mediated by Gq and G11 (Gq/11) and the other by G12 and G13 (G12/13), are implicated in the force-dependent activation of tr...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Association for the Advancement of Science
2016
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| Online Access: | http://eprints.nottingham.ac.uk/50300/ http://eprints.nottingham.ac.uk/50300/ http://eprints.nottingham.ac.uk/50300/ http://eprints.nottingham.ac.uk/50300/1/aad5568_Accepted.pdf |