Water solubility enhancement of pyrazolo[3,4-d]pyrimidine derivatives via miniaturized polymer-drug microarrays
A miniaturized assay was optimized to evaluate the enhanced apparent water solubility of pyrazolo[3,4-d]pyrimidine derivatives used extensively as anticancer drug scaffolds. The applied amount of drugs used in the reported strategy ranged from 5-10 μg per formulation which were dispensed by an inkje...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society
2018
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| Online Access: | http://eprints.nottingham.ac.uk/49478/ http://eprints.nottingham.ac.uk/49478/ http://eprints.nottingham.ac.uk/49478/ http://eprints.nottingham.ac.uk/49478/1/acsmedchemlett.7b00456.pdf |