Carbene footprinting reveals binding interfaces of a multimeric membrane spanning protein
Mapping the interaction sites between membrane spanning proteins is a key challenge in structural biology. In this study a carbene footprinting approach is developed and applied to identify the interfacial sites of a trimeric, integral membrane protein, OmpF, solubilised in micelles. The diazirine-b...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley-VCH Verlag
2017
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| Online Access: | http://eprints.nottingham.ac.uk/46932/ http://eprints.nottingham.ac.uk/46932/ http://eprints.nottingham.ac.uk/46932/ http://eprints.nottingham.ac.uk/46932/1/OmpF%20Footprinting%20manuscript.pdf |