Cediranib or placebo in combination with cisplatin and gemcitabine chemotherapy for patients with advanced biliary tract cancer (ABC-03): a randomised phase 2 trial

Cediranib or placebo in combination with cisplatin and gemcitabine chemotherapy for patients with advanced biliary tract cancer (ABC-03): a randomised phase 2 trial

BACKGROUND: Cisplatin and gemcitabine is the standard first-line chemotherapy regimen for patients with advanced biliary tract cancer; expression of VEGF and its receptors is associated with adverse outcomes. We aimed to assess the effect of the addition of cediranib (an oral inhibitor of VEGF recep...

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Main Authors: Valle, Juan W., Wasan, Harpreet, Lopes, Andre, Backen, Alison C., Palmer, Daniel H., Morris, Karen, Duggan, Marian, Cunningham, David, Anthoney, D. Alan, Corrie, Pippa, Srinivasan, Narayanan, Maraveyas, Anthony, Ross, Paul J., Waters, Justin S., Steward, Will P., Rees, Charlotte, Beare, Sandy, Dive, Caroline, Bridgewater, John A.
Format: Article
Language:English
Published: Elsevier 2015
Online Access:http://eprints.nottingham.ac.uk/43065/
http://eprints.nottingham.ac.uk/43065/
http://eprints.nottingham.ac.uk/43065/
http://eprints.nottingham.ac.uk/43065/1/lancet_oncology_2015_1.pdf

Internet

http://eprints.nottingham.ac.uk/43065/
http://eprints.nottingham.ac.uk/43065/
http://eprints.nottingham.ac.uk/43065/
http://eprints.nottingham.ac.uk/43065/1/lancet_oncology_2015_1.pdf

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